Important Safety Information

Before taking RHAPSIDO, tell your health care provider about all of your medical conditions, including if you:<ul><li>Have had a recent surgery or plan to have surgery. Your health care provider may tell you to stop taking RHAPSIDO for at least 3 to 7 days before and after any planned medical or surgical procedures</li><li>Have bleeding problems or are taking a blood thinner medicine</li><li>Have liver problems</li><li>Are pregnant or plan to become pregnant. It is not known if RHAPSIDO will harm your unborn baby. If you become pregnant during treatment with RHAPSIDO, talk to your health care provider about registering in the pregnancy exposure registry for RHAPSIDO</li><li>Are breastfeeding or plan to breastfeed. It is not known if RHAPSIDO passes into your breast milk</li><li>Have recently received or are scheduled to receive an immunization (vaccine). Talk to your health care provider about receiving any immunizations before taking RHAPSIDO. You should not receive live or live-attenuated vaccines during treatment with RHAPSIDO</li></ul>Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking RHAPSIDO with certain other medications may affect how RHAPSIDO or your other medications work, and can cause side effects.What are possible side effects of RHAPSIDO?RHAPSIDO may cause serious side effects, including:<ul><li>Risk of bleeding. Bleeding may happen while being treated with RHAPSIDO. Your health care provider will monitor you for signs and symptoms of bleeding and may stop your treatment if bleeding happens. Your risk of bleeding may increase if you are also taking a blood thinner medicine. Tell your health care provider right away if you get any signs or symptoms of bleeding, such as: o&nbsp;&nbsp;&nbsp;&nbsp;Bruising or red or purple skin marks o&nbsp;&nbsp;&nbsp;&nbsp;Pink or brown urine o&nbsp;&nbsp;&nbsp;&nbsp;Headache, dizziness, confusion, or feeling weak o&nbsp;&nbsp;&nbsp;&nbsp;Red or black stools that look like tar</li></ul>The most common side effects with RHAPSIDO may include nasal congestion, sore throat, and runny nose (nasopharyngitis), bleeding, headache, nausea, and abdominal pain.&nbsp;These are not all the possible side effects of RHAPSIDO.&nbsp;Call your health care provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <a href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>, or call 1-800-FDA-1088. &nbsp;Please see full <a href="https://www.novartis.com/us-en/sites/novartis_us/files/rhapsido.pdf" target="_blank">Prescribing Information</a>, including <a href="https://www.novartis.com/us-en/sites/novartis_us/files/rhapsido_ppi.pdf" target="_blank">Patient Information</a>.&nbsp;

What is RHAPSIDO?RHAPSIDO is a prescription medicine used to treat adults with chronic spontaneous urticaria (CSU) who continue to have symptoms that are not controlled with antihistamine treatment. RHAPSIDO should not be used to treat any other forms of hives (urticaria). It is not known if RHAPSIDO is safe and effective in children.

Approved Use

Before taking RHAPSIDO, tell your health care provider about all of your medical conditions, including if you:<ul><li>Have had a recent surgery or plan to have surgery. Your health care provider may tell you to stop taking RHAPSIDO for at least 3 to 7 days before and after any planned medical or surgical procedures</li><li>Have bleeding problems or are taking a blood thinner medicine</li></ul>

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