

Spot the symptoms
Patient portrayal.
When hives and itch are unpredictable, understanding brings clarity
Hives that return. Itch that lingers. Swelling that appears without warning. Recognizing these symptoms is the first step toward finding answers.
The main symptoms of chronic hives with no known external triggers
For many, a diagnosis of chronic hives with no known external triggers can take up to 2 years. Recognizing the signs and symptoms and sharing them with your doctor may help you reach meaningful relief sooner.
Chronic nature
One of the key distinguishing factors of chronic hives with no known external triggers from other forms of hives is that it lasts at least 6 weeks. While the symptoms can change on a day-to-day basis, if they occur for more than 6 weeks, this qualifies as chronic hives with no known external triggers. Because this is a chronic condition, it is important to speak to your doctor about a long-term treatment plan.
Itchy hives
Hives are red or skin-colored raised, itchy bumps on the outer layer of skin that usually resolve within 30 minutes to 24 hours. They can appear and disappear daily or almost daily without warning.
Hives can vary in both severity and appearance. See how hives can appear across various skin tones and differing levels of severity.
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Images are for illustrative purposes only and do not represent all skin types or hive presentations. This content is not medical advice.
Swelling
Severe swelling, also called angioedema, occurs in deeper layers of skin on the lips, eyelids, hands, feet, and other areas. It can last up to 72 hours.
Approximately 40% to 50% of people with chronic hives with no known external triggers experience swelling. Explore some of the most frequent forms of swelling associated with chronic hives with no known external triggers.
Swelling can vary in both severity and location. See the common places swelling can occur and how it may appear.
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Images are for illustrative purposes only and do not represent all skin types or swelling presentations. This content is not medical advice.
Relief with RHAPSIDO® (remibrutinib)
If antihistamines alone fall short, cut to RHAPSIDO.
RHAPSIDO should not be used to treat any other forms of hives.
A tool to stay on top of your symptoms
Tracking your symptoms and management approaches is an invaluable way to have more productive conversations with your doctor. Download the My Hives and Itch Tracker for a free, easy-to-use template to get started.

"I encourage people living with this condition to speak up about their needs. Ask questions and seek support."
– Lauren, a real patient living with CSU taking RHAPSIDO
Your CSU journey matters.
If you would like to share your experience with this condition and treatment with RHAPSIDO, please contact us at [email protected] or call 1-877-879-0245. A member of our Voices of Inspiration team will reach out to connect.






